Diabetes & Metabolism Journal

Original Articles

The Effects of Resistance Training on Muscle and Body Fat Mass and Muscle Strength in Type 2 Diabetic Women: Hwi Ryun Kwon, Kyung Ah Han, Yun Hyi Ku, Hee Jung Ahn, Bo-Kyung Koo, Ho Chul Kim, Kyung Wan Min; Korean Diabetes J. 2010;34(2):101-110. Published online April 30, 2010; DOI: https://doi.org/10.4093/kdj.2010.34.2.101

4,968 View
73 Download
55 Crossref

Background

Our goal was to investigate the effects of low intensity resistance training on body fat, muscle mass and strength, cardiovascular fitness, and insulin sensitivity in type 2 diabetes.

Methods

Twenty-eight overweight women with type 2 diabetes were randomly assigned to a resistance training group (RG, n = 13) or a control group (CG, n = 15). RG performed resistance training using elastic bands, of which strength was equal to 40 to 50% of one repetition maximum (1RM), for three days per week. Each exercise consisted of three sets for 60 minutes. We assessed abdominal fat using computed tomography, muscle mass using dual-energy X-ray absorptiometry, and muscle strength using Keiser's chest and leg press. Insulin sensitivity was measured using the insulin tolerance test, and aerobic capacity was expressed as oxygen uptake at the anaerobic threshold (AT-VO₂) before and after the 12-week exercise program.

Results

The age of participants was 56.4 ± 7.1 years, duration of diabetes was 5.9 ± 5.5 years, and BMI was 27.4 ± 2.5 kg/m², without significant differences between two groups. During intervention, a greater increase in muscle mass and greater decreases in both total fat mass and abdominal fat were observed in RG compared to those of CG (P = 0.015, P = 0.011, P = 0.010, respectively). Increase in 1RM of upper and lower extremities was observed in the RG (P = 0.004, P = 0.040, respectively), without changes in AT-VO₂ and insulin resistance in either group.

Conclusion

In conclusion, the low intensity resistance training was effective in increasing muscle mass and strength and reducing total fat mass without change of insulin sensitivity in type 2 diabetic patients.

Citations

Citations to this article as recorded by

The Impact of Resistance Exercise Training on Glycemic Control Among Adults with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Yuwen Wan, Zhanguo Su
Biological Research For Nursing.2024;[Epub] CrossRef
Current trends in the development of soy-based foods containing probiotics and paving the path for soy-synbiotics
Minnu Sasi, Sandeep Kumar, Muzaffar Hasan, Arpitha S. R., Enriqueta Garcia-Gutierrez, Sweta Kumari, Om Prakash, Lata Nain, Archana Sachdev, Anil Dahuja
Critical Reviews in Food Science and Nutrition.2023; 63(29): 9995. CrossRef
Communication Strategies and Resources for Health and Fitness Professionals to Minimize Diabetes-Related Social Stigma
Lindsay J. Della, Annika Reitenga, Kristi M. King
ACSM'S Health & Fitness Journal.2023; 27(2): 54. CrossRef
IMPACTS OF MUSCLE TRAINING LOADS ON COLLEGE STUDENTS' PHYSICAL FITNESS
Wang Lu, Zheng Hua, Wang Tailin, Wei Xuanxi
Revista Brasileira de Medicina do Esporte.2023;[Epub] CrossRef
Effect of resistance training on HbA1c in adults with type 2 diabetes mellitus and the moderating effect of changes in muscular strength: a systematic review and meta-analysis
Anna K Jansson, Li X Chan, David R Lubans, Mitch J Duncan, Ronald C Plotnikoff
BMJ Open Diabetes Research & Care.2022; 10(2): e002595. CrossRef
Role of genetic factors (biology of telomeres) in cardiac rehabilitation
D. M. Aronov, O. M. Drapkina, M. G. Bubnova
Cardiovascular Therapy and Prevention.2022; 21(6): 3272. CrossRef
Effects of 12-Week Progressive Sandbag Exercise Training on Glycemic Control and Muscle Strength in Patients with Type 2 Diabetes Mellitus Combined with Possible Sarcopenia
Yu-Hsuan Chien, Chia-Jen Tsai, Dean-Chuan Wang, Pin-Hung Chuang, Hwai-Ting Lin
International Journal of Environmental Research and Public Health.2022; 19(22): 15009. CrossRef
Effects of Online Live Pilates Training during the COVID-19 Pandemic on Body Composition, Cardiovascular Function, and Physical Fitness in Sedentary Middle-aged Obese Women
Jung-Heon Choi, Ko-Eun Choi, Man-Gyoon Lee
Korean Journal of Sport Science.2022; 33(4): 521. CrossRef
Muscular Strength, Functional Fitness, Body Composition, and Quality of Life after 12 Weeks of Detraining in Older Females
Matúš Krčmár, Nora Halmová, Jaroslav Krajčovič, Bohumila Krčmárová
Physical & Occupational Therapy In Geriatrics.2021; 39(2): 129. CrossRef
Comparison between different types of exercise training in patients with type 2 diabetes mellitus: A systematic review and network metanalysis of randomized controlled trials
Edoardo Mannucci, Allegra Bonifazi, Matteo Monami
Nutrition, Metabolism and Cardiovascular Diseases.2021; 31(7): 1985. CrossRef
DETERMINING NEW ANTHROPOMETRIC MARKERS FOR SCREENING TYPE 2 DM IN A CARIBBEAN REGION.
Amruta Rajput, Upendra K Gupta, Guri Tzivion, Ravindrasingh Rajput
INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH.2021; : 58. CrossRef
Effect of elastic band resistance training with green coffee extract supplementation on adiposity indices and TyG-related Indicators in Obese Women
Zahra Rashidi, Rezvan Beigi, Majid Mardaniyan Ghahfarrokhi, Mohammad Faramarzi, Ebrahim Banitalebi, Tina Jafari, Conrad P. Earnest, Julien S. Baker
Obesity Medicine.2021; 24: 100351. CrossRef
Effect of resistance training with and without caloric restriction on visceral fat: A systemic review and meta‐analysis
Mousa Khalafi, Abbas Malandish, Sara K. Rosenkranz, Ali A. Ravasi
Obesity Reviews.2021;[Epub] CrossRef
The Effect of Elastic Resistance Band Training on Postural Control and Body Composition in Sedentary Women
Yağmur KOCAOĞLU, Nurtekin ERKMEN
Spor Bilimleri Araştırmaları Dergisi.2021; 6(1): 233. CrossRef
Strength Training and Insulin Resistance: The Mediating Role of Body Composition
McKayla J. Niemann, Larry A. Tucker, Bruce W. Bailey, Lance E. Davidson
Journal of Diabetes Research.2020; 2020: 1. CrossRef
Beyond general resistance training. Hypertrophy versus muscular endurance training as therapeutic interventions in adults with type 2 diabetes mellitus: A systematic review and meta‐analysis
Pedro Acosta‐Manzano, María Rodriguez‐Ayllon, Francisco M. Acosta, David Niederseer, Josef Niebauer
Obesity Reviews.2020;[Epub] CrossRef
Resistance Exercise Intensity is Correlated with Attenuation of HbA1c and Insulin in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Yubo Liu, Weibing Ye, Qian Chen, Yong Zhang, Chia-Hua Kuo, Mallikarjuna Korivi
International Journal of Environmental Research and Public Health.2019; 16(1): 140. CrossRef
Effectiveness of Exercise Intervention in Reducing Body Weight and Glycosylated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus in Korea: A Systematic Review and Meta-Analysis
Ji-Eun Jang, Yongin Cho, Byung Wan Lee, Ein-Soon Shin, Sun Hee Lee
Diabetes & Metabolism Journal.2019; 43(3): 302. CrossRef
Effects of a moderate-to-high intensity resistance circuit training on fat mass, functional capacity, muscular strength, and quality of life in elderly: A randomized controlled trial
Pablo Jorge Marcos-Pardo, Francisco Javier Orquin-Castrillón, Gemma María Gea-García, Ruperto Menayo-Antúnez, Noelia González-Gálvez, Rodrigo Gomes de Souza Vale, Alejandro Martínez-Rodríguez
Scientific Reports.2019;[Epub] CrossRef
Effects of Resistance Exercise on Glycated Hemoglobin and Functional Performance in Older Patients with Comorbid Diabetes Mellitus and Knee Osteoarthritis: A Randomized Trial
Shu-Mei Chen, Feng-Chih Shen, Jung-Fu Chen, Wen-Dien Chang, Nai-Jen Chang
International Journal of Environmental Research and Public Health.2019; 17(1): 224. CrossRef
Effects of low‐intensity resistance training on muscular function and glycemic control in older adults with type 2 diabetes
Eri Takenami, ShinMin Iwamoto, Noriko Shiraishi, Akiko Kato, Yuichi Watanabe, Yoshifumi Yamada, Satoru Yamada, Naokata Ishii
Journal of Diabetes Investigation.2019; 10(2): 331. CrossRef
Effect of 12-Month Resistance Training on Changes in Abdominal Adipose Tissue and Metabolic Variables in Patients with Prediabetes: A Randomized Controlled Trial
Juan Yan, Xia Dai, Jitao Feng, Xiaodan Yuan, Jianing Li, Lihong Yang, Panpan Zuo, Zhaohui Fang, Chao Liu, Cunyi Hsue, Junya Zhu, Joshua D. Miller, Qingqing Lou
Journal of Diabetes Research.2019; 2019: 1. CrossRef
Positive Effects of a Short-Term Intense Elastic Resistance Training Program on Body Composition and Physical Functioning in Overweight Older Women
Nicole B. Fritz, Álvaro Juesas, Pedro Gargallo, Joaquín Calatayud, Julio Fernández-Garrido, Michael E. Rogers, Juan C. Colado
Biological Research For Nursing.2018; 20(3): 321. CrossRef
Protein timing during the day and its relevance for muscle strength and lean mass
Samuel L. Buckner, Jeremy P. Loenneke, Paul D. Loprinzi
Clinical Physiology and Functional Imaging.2018; 38(2): 332. CrossRef
Exercise training modalities in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis
Bei Pan, Long Ge, Yang-qin Xun, Ya-jing Chen, Cai-yun Gao, Xue Han, Li-qian Zuo, Hou-qian Shan, Ke-hu Yang, Guo-wu Ding, Jin-hui Tian
International Journal of Behavioral Nutrition and Physical Activity.2018;[Epub] CrossRef
Resistance training reduces metabolic syndrome and inflammatory markers in older women: A randomized controlled trial
Crisieli M. Tomeleri, Mariana F. Souza, Roberto C. Burini, Cláudia R. Cavaglieri, Alex S. Ribeiro, Melissa Antunes, João P. Nunes, Danielle Venturini, Décio S. Barbosa, Luís B. Sardinha, Edilson S. Cyrino
Journal of Diabetes.2018; 10(4): 328. CrossRef
Effect of Resistance Training with Blood Flow Restriction on Follistatin to Myostatin Ratio, Body Composition and Anaerobic Power of Trained-Volleyball Players
Reza Bagheri, Amir Rashidlamir, Seyyed Reza Attarzadeh Hosseini
Medical Laboratory Journal.2018; 12(6): 28. CrossRef
Effects of 8-week kettlebell training on body composition, muscle strength, pulmonary function, and chronic low-grade inflammation in elderly women with sarcopenia
Hung-Ting Chen, Huey-June Wu, Yu-Jen Chen, Sung-Yen Ho, Yu-Chun Chung
Experimental Gerontology.2018; 112: 112. CrossRef
F inding the O ptimal volume and intensity of R esistance T raining E xercise for Type 2 Diabetes: The FORTE Study, a Randomized Trial
Pearl Yang, Walter Swardfager, Daniel Fernandes, Sheila Laredo, George Tomlinson, Paul I. Oh, Scott Thomas
Diabetes Research and Clinical Practice.2017; 130: 98. CrossRef
Exercise and ectopic fat in type 2 diabetes: A systematic review and meta-analysis
A. Sabag, K.L. Way, S.E. Keating, R.N. Sultana, H.T. O’Connor, M.K. Baker, V.H. Chuter, J. George, N.A. Johnson
Diabetes & Metabolism.2017; 43(3): 195. CrossRef
Resistance training to improve type 2 diabetes: working toward a prescription for the future
Dominik H. Pesta, Renata L. S. Goncalves, Anila K. Madiraju, Barbara Strasser, Lauren M. Sparks
Nutrition & Metabolism.2017;[Epub] CrossRef
Improvement of obesity-linked skeletal muscle insulin resistance by strength and endurance training
Sergio Di Meo, Susanna Iossa, Paola Venditti
Journal of Endocrinology.2017; 234(3): R159. CrossRef
Leisure time sedentary behavior, physical activity and frequency of protein consumption on lower extremity strength and lean mass
P D Loprinzi, J P Loenneke, D L Hamilton
European Journal of Clinical Nutrition.2017; 71(12): 1399. CrossRef
Strength Training Prevents Hyperinsulinemia, Insulin Resistance, and Inflammation Independent of Weight Loss in Fructose-Fed Animals
José D. Botezelli, Andressa Coope, Ana C. Ghezzi, Lucieli T. Cambri, Leandro P. Moura, Pedro P. M. Scariot, Rodrigo Stellzer Gaspar, Rania A. Mekary, Eduardo Rochete Ropelle, José Rodrigo Pauli
Scientific Reports.2016;[Epub] CrossRef
Effects of Elastic Band Resistance Training on Glucose Control, Body Composition, and Physical Function in Women With Short- vs. Long-Duration Type-2 Diabetes
Bong-Sup Park, Andy V. Khamoui, Lee E. Brown, Do-Youn Kim, Kyung-Ah Han, Kyung-Wan Min, Geun-Hee An
Journal of Strength and Conditioning Research.2016; 30(6): 1688. CrossRef
Neuromuscular dysfunction in type 2 diabetes: underlying mechanisms and effect of resistance training
Giorgio Orlando, Stefano Balducci, Ilenia Bazzucchi, Giuseppe Pugliese, Massimo Sacchetti
Diabetes/Metabolism Research and Reviews.2016; 32(1): 40. CrossRef
Physical exercises with free weights and elastic bands can improve body composition parameters in postmenopausal women
Simoni T. Bittar, Sergio S. Maeda, Marília M.S. Marone, Cláudio Santili
Menopause.2016; 23(4): 383. CrossRef
Effects of exercise training using resistance bands on glycaemic control and strength in type 2 diabetes mellitus: a meta-analysis of randomised controlled trials
Samantha K. McGinley, Marni J. Armstrong, Normand G. Boulé, Ronald J. Sigal
Acta Diabetologica.2015; 52(2): 221. CrossRef
Effect of exercise training on neuromuscular function of elbow flexors and knee extensors of type 2 diabetic patients
I. Bazzucchi, G. De Vito, F. Felici, S. Dewhurst, A. Sgadari, M. Sacchetti
Journal of Electromyography and Kinesiology.2015; 25(5): 815. CrossRef
Effects of short term elastic resistance training on muscle mass and strength in untrained older adults: a randomized clinical trial
Wagner Rodrigues Martins, Marisete Peralta Safons, Martim Bottaro, Juscelino Castro Blasczyk, Leonardo Rios Diniz, Romulo Maia Carlos Fonseca, Ana Clara Bonini-Rocha, Ricardo Jacó de Oliveira
BMC Geriatrics.2015;[Epub] CrossRef
Brain-derived neurotrophic factor correlated with muscle strength in subjects undergoing stationary bicycle exercise training
Sen-Wei Tsai, Yin-Ching Chan, Francois Liang, Chiann-Yi Hsu, I-Te Lee
Journal of Diabetes and its Complications.2015; 29(3): 367. CrossRef
Implementation of Resources to Support Patient Physical Activity through Diabetes Centres in Nova Scotia: The Effectiveness of Enhanced Support for Exercise Participation
Jonathon R. Fowles, Chris Shields, Lisette d’Entremont, Stephanie McQuaid, Brittany Barron, Peggy Dunbar
Canadian Journal of Diabetes.2014; 38(6): 423. CrossRef
Changes in insulin sensitivity in response to different modalities of exercise: a review of the evidence
S. Mann, C. Beedie, S. Balducci, S. Zanuso, J. Allgrove, F. Bertiato, A. Jimenez
Diabetes/Metabolism Research and Reviews.2014; 30(4): 257. CrossRef
The surprising influence of family history to type 2 diabetes on anaerobic performance of young male élite athletes
Antonino Bianco, Francesco Pomara, Antonino Patti, Ewan Thomas, Marco Petrucci, Marianna Bellafiore, Giuseppe Battaglia, Antonio Paoli, Antonio Palma
SpringerPlus.2014;[Epub] CrossRef
Skeletal muscle and organ masses differ in overweight adults with type 2 diabetes
Lance E. Davidson, David E. Kelley, Stanley Heshka, John Thornton, F. Xavier Pi-Sunyer, Lawrence Boxt, Ashok Balasubramanyam, Dympna Gallagher
Journal of Applied Physiology.2014; 117(4): 377. CrossRef
The effects of elastic band resistance training combined with blood flow restriction on strength, total bone‐free lean body mass and muscle thickness in postmenopausal women
Robert S. Thiebaud, Jeremy P. Loenneke, Christopher A. Fahs, Lindy M. Rossow, Daeyeol Kim, Takashi Abe, Mark A. Anderson, Kaelin C. Young, Debra A. Bemben, Michael G. Bemben
Clinical Physiology and Functional Imaging.2013; 33(5): 344. CrossRef
Predicting Aerobic Fitness Improvements after Participation in a Hybrid Supervised and Home-Based Exercise Program in People with Type 2 Diabetes
Pearl Yang, Paul Oh
Canadian Journal of Diabetes.2013; 37(6): 388. CrossRef
Impacto do treinamento resistido na força e hipertrofia muscular em HIV-soropositivos
Ciro José Brito, Edmar Lacerda Mendes, Aparecido Pimentel Ferreira, Sérgio Oliveira De Paula, Otávio de Tolêdo Nóbrega, Cláudio Córdova
Motriz: Revista de Educação Física.2013; 19(2): 313. CrossRef
Resistance Training for Diabetes Prevention and Therapy: Experimental Findings and Molecular Mechanisms
Barbara Strasser, Dominik Pesta
BioMed Research International.2013; 2013: 1. CrossRef
Resistance training, visceral obesity and inflammatory response: a review of the evidence
B. Strasser, M. Arvandi, U. Siebert
Obesity Reviews.2012; 13(7): 578. CrossRef
The effects of resistance training on ApoB/ApoA-I ratio, Lp(a) and inflammatory markers in patients with type 2 diabetes
Nikolaos P. E. Kadoglou, Grigorios Fotiadis, Zoi Athanasiadou, Ioulia Vitta, Stylianos Lampropoulos, Ioannis S. Vrabas
Endocrine.2012; 42(3): 561. CrossRef
A systematic review and meta‐analysis of the effect of aerobic vs. resistance exercise training on visceral fat
I. Ismail, S. E. Keating, M. K. Baker, N. A. Johnson
Obesity Reviews.2012; 13(1): 68. CrossRef
Aging, Resistance Training, and Diabetes Prevention
Kyle D. Flack, Kevin P. Davy, Matthew W. Hulver, Richard A. Winett, Madlyn I. Frisard, Brenda M. Davy
Journal of Aging Research.2011; 2011: 1. CrossRef
The Effects of Aerobic/Resistance Exercise on Body Fat Mass, Muscle Strength and Endothelial Function in Korean Type 2 Diabetes mellitus Patients
Kyung Wan Min
Journal of Korean Diabetes.2011; 12(1): 6. CrossRef
Exercise and Type 2 Diabetes
Sheri R. Colberg, Ronald J. Sigal, Bo Fernhall, Judith G. Regensteiner, Bryan J. Blissmer, Richard R. Rubin, Lisa Chasan-Taber, Ann L. Albright, Barry Braun
Diabetes Care.2010; 33(12): e147. CrossRef

Effects of Aerobic Exercise on Abdominal Fat, Thigh Muscle Mass and Muscle Strength in Type 2 Diabetic Subject: Hwi Ryun Kwon, Kyung Wan Min, Hee Jung Ahn, Hee Geum Seok, Bo Kyung Koo, Ho Chul Kim, Kyung Ah Han; Korean Diabetes J. 2010;34(1):23-31. Published online February 28, 2010; DOI: https://doi.org/10.4093/kdj.2010.34.1.23

3,652 View
43 Download
18 Crossref

Abstract PDF PubReader

Background

Aerobic exercise can effectively reduce visceral fat. However, few studies have examined the effect of daily physical activity on obesity and cardiopulmonary function in the subjects with diabetes. We examined the effect of moderate intensity of walking in obese diabetes patients by monitoring of daily activity and measuring the change in abdominal fat area, muscle are and maximal muscle strength.

Methods

We randomly assigned 27 obese women with type 2 diabetes to an aerobic exercise group (AG, n = 13) and control group (CG, n = 14). The AG performed moderate intensity walking for 60 minutes per exercise, 5 times per week, and for 12 weeks. The activity energy expenditure was monitored by a multi-record accelerometer. The CG maintained routine daily activities. At the time of the initiation of the study and after 12 weeks of exercise, the aerobic exercise capacity was assessed using oxygen consumption rate at anaerobic threshold (VO₂-AT). The abdominal fat area and the quadriceps muscle area were measured by computed tomography, and the maximum muscle strength of the upper and lower limbs was measured by a chest press and a leg press, respectively.

Results

The mean age of the study subjects was 56.6 ± 8.0 years, the mean duration of diabetes was 6.3 ± 6.0 years, and the body weight index (BMI) was 27.3 ± 2.7 kg/m². The BMI of the AG was significantly decreased (P = 0.003). In the AG, the visceral fat area and subcutaneous fat area were also significantly decreased (P = 0.018 and P < 0.001, respectively) but not in CG. VO₂-AT of the AG was significantly improved, while that of the CG did not change (P = 0.009 and P = 0.115, respectively). The quadriceps muscle mass and the maximal muscle strength of the AG did not change, however, the CG showed a significant decrease. Duration of moderate intensity exercise was correlated with the decrease in total abdominal fat area (r = -0.484; P = 0.011) and that of high intensity exercise was correlated with improvement of cardiopulmonary function (r = 0.414; P = 0.032).

Conclusion

Daily moderate intensity aerobic exercise is effective at reducing abdominal fat mass, while high intensity exercise improves cardiopulmonary function.

Citations

Citations to this article as recorded by

Relationship Between Visceral Fat Tissue and Exercise
Ebru Ceviz
Türk Spor Bilimleri Dergisi.2024;[Epub] CrossRef
Walking for subjects with type 2 diabetes: a systematic review and joint AMD/SID/SISMES evidence-based practical guideline
P. Moghetti, S. Balducci, L. Guidetti, P. Mazzuca, E. Rossi, F. Schena, P. Moghetti, S. Balducci, L. Guidetti, F. Schena, P. Mazzuca, E. Rossi
Sport Sciences for Health.2021; 17(1): 1. CrossRef
Effect of exercise intervention dosage on reducing visceral adipose tissue: a systematic review and network meta-analysis of randomized controlled trials
Yu-Hsuan Chang, Hui-Ying Yang, Shiow-Ching Shun
International Journal of Obesity.2021; 45(5): 982. CrossRef
Comparison between different types of exercise training in patients with type 2 diabetes mellitus: A systematic review and network metanalysis of randomized controlled trials
Edoardo Mannucci, Allegra Bonifazi, Matteo Monami
Nutrition, Metabolism and Cardiovascular Diseases.2021; 31(7): 1985. CrossRef
The Therapeutic Effects of Mild to Moderate Intensity Aerobic Exercise on Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Trials
Siyao Gao, Jialing Tang, Guozhong Yi, Zhong Li, Zhenyin Chen, Ling Yu, Feng Zheng, Yajing Hu, Zhangui Tang
Diabetes Therapy.2021; 12(10): 2767. CrossRef
Walking for subjects with type 2 diabetes: A systematic review and joint AMD/SID/SISMES evidence-based practical guideline
P. Moghetti, S. Balducci, L. Guidetti, P. Mazzuca, E. Rossi, F. Schena
Nutrition, Metabolism and Cardiovascular Diseases.2020; 30(11): 1882. CrossRef
Effect of Coordinative Locomotor Training Program on Body Fat and Muscle mass of Male University students
Hyung chun Nam, Nam jeong Cho, Jae yong Choi
Archives of Orthopedic and Sports Physical Therapy.2019; 15(2): 109. CrossRef
Exercise training modalities in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis
Bei Pan, Long Ge, Yang-qin Xun, Ya-jing Chen, Cai-yun Gao, Xue Han, Li-qian Zuo, Hou-qian Shan, Ke-hu Yang, Guo-wu Ding, Jin-hui Tian
International Journal of Behavioral Nutrition and Physical Activity.2018;[Epub] CrossRef
Exercise and ectopic fat in type 2 diabetes: A systematic review and meta-analysis
A. Sabag, K.L. Way, S.E. Keating, R.N. Sultana, H.T. O’Connor, M.K. Baker, V.H. Chuter, J. George, N.A. Johnson
Diabetes & Metabolism.2017; 43(3): 195. CrossRef
A systematic review and meta‐analysis on the effects of exercise training versus hypocaloric diet: distinct effects on body weight and visceral adipose tissue
R. J. H. M. Verheggen, M. F. H. Maessen, D. J. Green, A. R. M. M. Hermus, M. T. E. Hopman, D. H. T. Thijssen
Obesity Reviews.2016; 17(8): 664. CrossRef
Effects of Aerobic Exercise Associated with Abdominal Microcurrent: A Preliminary Study
Andreia Noites, Rita Nunes, Ana Isabel Gouveia, Alexandra Mota, Cristina Melo, Ágata Viera, Nuno Adubeiro, José Mesquita Bastos
The Journal of Alternative and Complementary Medicine.2015; 21(4): 229. CrossRef
Brain-derived neurotrophic factor correlated with muscle strength in subjects undergoing stationary bicycle exercise training
Sen-Wei Tsai, Yin-Ching Chan, Francois Liang, Chiann-Yi Hsu, I-Te Lee
Journal of Diabetes and its Complications.2015; 29(3): 367. CrossRef
Impact of Walking on Glycemic Control and Other Cardiovascular Risk Factors in Type 2 Diabetes: A Meta-Analysis
Shanhu Qiu, Xue Cai, Uwe Schumann, Martina Velders, Zilin Sun, Jürgen Michael Steinacker, Lamberto Manzoli
PLoS ONE.2014; 9(10): e109767. CrossRef
A systematic review and meta‐analysis of the effect of aerobic vs. resistance exercise training on visceral fat
I. Ismail, S. E. Keating, M. K. Baker, N. A. Johnson
Obesity Reviews.2012; 13(1): 68. CrossRef
The Effects of Regular Pilates Exercise on Blood pressure and Pulmonary Variables
Gyu-Chang Lee, Dong-Yeop Lee, Jae-Ho Yu
Journal of the Korea Academia-Industrial cooperation Society.2011; 12(7): 3088. CrossRef
The Effects of Aerobic/Resistance Exercise on Body Fat Mass, Muscle Strength and Endothelial Function in Korean Type 2 Diabetes mellitus Patients
Kyung Wan Min
Journal of Korean Diabetes.2011; 12(1): 6. CrossRef
The Evaluation of Workplace Obesity Intervention Program using Six Sigma Methodology
Ji Yeon Kang, Ill Keun Park, Yun Kyun Chang, Sook Hee Sung, Yoo Kyoung Park, Sang Woon Cho, Yun Mi Paek, Tae In Choi
The Korean Journal of Obesity.2011; 20(4): 193. CrossRef
How Can We Measure the Effects of Exercise in Daily Life?
Sang Yong Kim
Korean Diabetes Journal.2010; 34(1): 21. CrossRef

Randomized Controlled Trial

Effects of Aerobic Exercise Intensity on Insulin Resistance in Patients with Type 2 Diabetes Mellitus.: Yun Hyi Ku, Bo Kyung Koo, Hee Jung Ahn, Ji Yun Jeong, Hee Geum Seok, Ho Chul Kim, Kyung Ah Han, Kyung Wan Min; Korean Diabetes J. 2009;33(5):401-411. Published online October 1, 2009; DOI: https://doi.org/10.4093/kdj.2009.33.5.401

2,843 View
38 Download
6 Crossref

Abstract PDF

BACKGROUND
Exercise offers protection against atherosclerosis and insulin resistance. We evaluated the benefits of exercise at different levels of intensity for ameliorating inflammation, endothelial dysfunction, and insulin resistance in a sample of type 2 diabetic subjects. METHODS: Fifty-nine overweight women with type 2 diabetes were randomly assigned to control (CG, N = 18), moderate-intensity exercise (MEG, N = 17), and vigorous-intensity exercise (VEG, N = 14) groups. Patients in the two experimental groups completed a 12-week exercise program, with their exercise activities monitored by accelerometers. We assessed the patients' body weights, total abdominal fat (TF), subcutaneous fat (SF) and visceral fat (VF) via computed tomography, measurements of plasma levels of hs-C-reactive protein (hs-CRP) and interleukin-6 (IL-6), assessment of endothelial function by brachial artery flow-mediated dilation (FMD), and evaluation of insulin sensitivity by insulin tolerance tests, at baseline, at the end of the 12-week interventions, and one year after initiation of the study. RESULTS: At baseline, the average age of all subjects was 54 +/- 7 years, and average body mass index (BMI) was 26.9 +/- 2.5 kg/m2. During the intervention, patients in the MEG and VEG groups expended comparable amounts of activity-related calories (488.6 +/- 111.9 kcal/day, 518.8 +/- 104.1 kcal/day, respectively). Although BMI, TF, and SF decreased similarly in the MEG and VEG groups (deltaBMI: -1.1 +/- 0.7, -0.8 +/- 0.5, deltaTF: -4,647 +/- 3,613 mm2, -2,577 +/- 2,872 mm2, deltaSF: -2,057 +/- 2,021 mm2, -1,141 +/- 1,825 mm2, respectively), compared to control (P<0.01), hs-CRP, IL-6, and FMD remained constant in both exercise groups even after completion of the 12-week exercise intervention. Insulin sensitivity improved only in patients subjected to vigorous exercise (VEG). Visceral fat loss was observed only in patients subjected to moderate exercise (MEG). At one-year follow up, these values had all returned to baseline. CONCLUSION: Exercise vigorous enough to result in significant weight and fat reduction did not ameliorate inflammation and endothelial dysfunction as measured at the end of a 12-week exercise intervention, nor did it result in sustained improvements in insulin sensitivity in type 2 diabetic subjects.

Citations

Citations to this article as recorded by

The anti-inflammatory effects of aerobic exercise training in patients with type 2 diabetes: A systematic review and meta-analysis
Georgia Papagianni, Chrystalla Panayiotou, Michail Vardas, Nikolaos Balaskas, Constantinos Antonopoulos, Dimitrios Tachmatzidis, Triantafyllos Didangelos, Vaia Lambadiari, Nikolaos P.E. Kadoglou
Cytokine.2023; 164: 156157. CrossRef
Effects of Exercise on Inflammatory Cytokines in Patients with Type 2 Diabetes: A Meta-analysis of Randomized Controlled Trials
Xiaoke Chen, Xinzheng Sun, Chenghao Wang, Hui He, Jos L. Quiles
Oxidative Medicine and Cellular Longevity.2020; 2020: 1. CrossRef
Effect of Diabetic Dietary Education Program on Diabetes Knowledge and Dietary Behaviors of Elderly Diabetic Patients
Ji Young Ye, Sung Hee Min, Min June Lee
Korean Journal of Food & Cookery Science.2017; 33(5): 601. CrossRef
Effect of aerobic exercise intensity on glycemic control in type 2 diabetes: a meta-analysis of head-to-head randomized trials
Yilina Liubaoerjijin, Tasuku Terada, Kevin Fletcher, Normand G. Boulé
Acta Diabetologica.2016; 53(5): 769. CrossRef
Letter: Effects of Aerobic Exercise Intensity on Insulin Resistance in Patients with Type 2 Diabetes Mellitus (Korean Diabetes J 33(5):401-411, 2009)
Dong-Lim Kim
Korean Diabetes Journal.2009; 33(6): 547. CrossRef
Response: Effects of Aerobic Exercise Intensity on Insulin Resistance in Patients with Type 2 Diabetes Mellitus (Korean Diabetes J 33:(5)401-411, 2009)
Yun Hyi Ku, Bo-Kyung Koo, Kyung-Wan Min
Korean Diabetes Journal.2009; 33(6): 549. CrossRef

First
Prev
Page of 1
Next
Last

Search